Pill can prevent fatal tb in hiv patients
An inexpensive daily pill can often fend off a lethal bout of tuberculosis in people with HIV, according to a large new study.
The drug is isoniazid, a generic
antibiotic, and the World Health Organisation has recommended a daily
dose since 1998 for HIV patients who harbor tuberculosis but have no
symptoms; full-blown TB is a leading killer of AIDS victims. But doctors
in poor countries rarely bother to offer it.
The study, published last week by Lancet
Infectious Disease, found that a daily isoniazid pill reduced deaths
and active TB cases by 31 percent among 12,816 patients at 29 Brazilian
clinics.
In patients whose urine samples proved that they took their pills regularly, the reduction was far greater: about 80 percent.
Side effects were minor, and of the
patients who developed TB despite taking the pill, none got an
isoniazid-resistant form of the disease.
An accompanying editorial said isoniazid
works, but only when clinics test patients correctly, provide pills
steadily and make sure they are taken.
US circumcision rates drop
The percentage of newborn boys who are
circumcised in the United States declined to 58.3 per cent in 2010 from
64.5 per cent in 1979, according to a new analysis from the National
Centre for Health Statistics.
The report is based on annual surveys of about 450 hospitals nationwide.
But rates varied over the period. They
went down during the 1980s after a task force of the American Academy of
Pediatrics found that there were no medical benefits to the procedure,
then rose during the ‘90s after the medical group revised its position,
claiming there were potential benefits.
In 1999, the academy changed its view
again, stating that despite potential benefits, there was insufficient
evidence to recommend routine circumcision.
That announcement was followed by another slight decrease.
There are regional variations as well.
In 2010, about 71 per cent of babies in the Midwest were circumcised,
66.3 per cent in the Northeast, 58.4 per cent in the South, and 40.2 per
cent in the West.
The lead author of the report, Maria
Owings, a health statistician with the center, emphasised that the
report includes no explanation for the numbers.
“We didn’t factor in any other
contextual information that would shed light on the reasons for the
regional variations or the variations over time,” she said.
And, she added, “The NCHS doesn’t take an advocacy position.”
New York Times Service
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